Novel Key Ingredients in Urinary Tract Health—The Role of D-mannose, Chondroitin Sulphate, Hyaluronic Acid, and N-acetylcysteine in Urinary Tract Infections (Uroial PLUS®)
Authors:
- Felice CrocettoFCFelice Crocetto
- Raffaele BalsamoRBRaffaele Balsamo
- Ugo AmicuziUAUgo Amicuzi
- Luigi De LucaLLLuigi De Luca
- Alfonso FalconeAFAlfonso Falcone
- Benito Fabio MirtoBMBenito Fabio Mirto
- Gaetano GiampagliaGGGaetano Giampaglia
- Gianpiero FerrettiGFGianpiero Ferretti
- Federico CaponeFCFederico Capone
- Fabio MachiellaFMFabio Machiella
- Domenico VarrialeDVDomenico Varriale
- Enrico SicignanoEnrico Sicignano
Open Access
Abstract
Urinary tract infections represent a common and significant health concern worldwide. The high rate of recurrence and the increasing antibiotic resistance of uropathogens are further worsening the current scenario. Nevertheless, novel key ingredients such as D-mannose, chondroitin sulphate, hyaluronic acid, and N-acetylcysteine could represent an important alternative or adjuvant to the prevention and treatment strategies of urinary tract infections. Several studies have indeed evaluated the efficacy and the potential use of these compounds in urinary tract health. In this review, we aimed to summarize the characteristics, the role, and the application of the previously reported compounds, alone and in combination, in urinary tract health, focusing on their potential role in urinary tract infections.Keywords
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