Asymmetric 1,4-Addition of Arylboronic Acids to α,β-Unsaturated Aldehydes Catalyzed by a Chiral Diene–Rhodium Complex
- 28 September 2005
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 34 (11) , 1480-1481
Abstract
Asymmetric 1,4-addition of arylboronic acids to α,β-unsaturated aldehydes proceeded in the presence of a rhodium catalyst (3 mol %) coordinated with a chiral diene ligand ((R,R)-Bn-bod*) to give the corresponding β-arylaldehydes with perfect 1,4-selectivity and with 88–97% enantioselectivity.Keywords
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