Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton
Authors:
- Siraj M AliSASiraj M Ali
- Do-Hyung KimDKDo-Hyung Kim
- David A GuertinDGDavid A Guertin
- Robert R LatekRLRobert R Latek
- Hediye Erdjument-BromageHEHediye Erdjument-Bromage
- Paul TempstPaul Tempst
- David M SabatiniDSDavid M Sabatini
Top Cited Papers
- 1 July 2004
- journal article
- research article
- Published by Elsevier in Current Biology
- Vol. 14 (14) , 1296-1302
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- GβL, a Positive Regulator of the Rapamycin-Sensitive Pathway Required for the Nutrient-Sensitive Interaction between Raptor and mTORMolecular Cell, 2003
- Lentivirus-delivered stable gene silencing by RNAi in primary cellsRNA, 2003
- Tor Kinases Are in Distinct Membrane-associated Protein Complexes inSaccharomyces cerevisiaeMolecular Biology of the Cell, 2003
- Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR ActionCell, 2002
- mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth MachineryCell, 2002
- Immunopurified Mammalian Target of Rapamycin Phosphorylates and Activates p70 S6 Kinase α in VitroJournal of Biological Chemistry, 1999
- The Yeast Phosphatidylinositol Kinase Homolog TOR2 Activates RHO1 and RHO2 via the Exchange Factor ROM2Cell, 1997
- Replacement of Ser657 of Protein Kinase C‐α by Alanine Leads to Premature Down Regulation After Phorbol‐Ester‐Induced Translocation to the MembraneEuropean Journal of Biochemistry, 1996
- Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinaseNature, 1992
- Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinasesCell, 1992