Low serum cholesterol levels and depressive state in human dock visitors

Authors:
  • TTT. Terao
    T. Terao
  • NIN. Iwata
    N. Iwata
  • KKK. Kanazawa
    K. Kanazawa
  • TTT. Takano
    T. Takano
  • NTN. Takahashi
    N. Takahashi
  • THT. Hayashi
    T. Hayashi
  • YSY. Sugawara
    Y. Sugawara
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Abstract
Objective: The purpose of the present study was to investigate an association between serum cholesterol levels and depressive state. Method: Physical examinations and mental assessments were performed for 13 702 human dock visitors. We obtained 13 571 sets of complete data for serum total cholesterol, the scores for depressive state and possible confounders such as sex, age, body weight, body mass index (BMI), recent weight loss, total protein and concomitant medical diagnoses. Results: Their depressive state varied significantly across the serum cholesterol levels after adjusting age and gender. After controlling all the above confounding variables the significance still remained, not only in the categorical analysis but also in the continuous analysis. Conclusion: The present findings suggest that there is an association between cholesterol and depressive state.