Evidence for Two Subtypes of Cushing's Disease Based on the Analysis of Episodic Cortisol Secretion
Authors:
- Eve Van CauterECEve Van Cauter
- Samuel RefetoffSRSamuel Refetoff
- 23 May 1985
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 312 (21) , 1343-1349
Abstract
To investigate the pathogenetic mechanisms of Cushing's syndrome, we studied variations in plasma Cortisol levels (episodic variations, or pulses) over 24 hours in 51 normal subjects, 14 patients with adrenal adenoma, and 46 patients with Cushing's disease. Data were obtained both from our patients and from the literature.Keywords
This publication has 32 references indexed in Scilit:
- The Effect of Dexamethasone on the 24-Hour Profiles of Adrenocorticotropin and Cortisol in Cushing's Syndrome*The Journal of Clinical Endocrinology & Metabolism, 1985
- The Corticotropin-Releasing Factor Stimulation TestNew England Journal of Medicine, 1984
- Physiopathology of Cushing's DiseaseEndocrine Reviews, 1983
- DEXAMETHASONE SUPPRESSION TESTS: USEFULNESS OF SIMULTANEOUS MEASUREMENT OF PLASMA CORTISOL AND DEXAMETHASONEClinical Endocrinology, 1982
- Cushingʼs Syndrome: Problems in DiagnosisMedicine, 1981
- Cushingʼs Disease—18 Yearsʼ ExperienceMedicine, 1981
- Some Methods for Studying the Mixture of Two Normal (Lognormal) DistributionsJournal of the American Statistical Association, 1979
- The Cushing Syndromes: Changing Views of Diagnosis and TreatmentAnnals of Internal Medicine, 1979
- Effects of Oral Contraceptive Therapy on the Orcadian Patterns of Cortisol and Thyrotropin (TSH)European Journal of Clinical Investigation, 1975
- Diurnal patterns of secretion of cortisol and growth hormone in normal adolescents, in patients with exogenous and endogenous Cushing's syndrome, in patients with diabetes mellitus, and in a fasting subjectThe Journal of Pediatrics, 1973