STX5 Inhibits Hepatocellular Carcinoma Adhesion and Promotes Metastasis by Regulating the PI3K/mTOR Pathway
Open Access
- 9 January 2023
- journal article
- research article
- Published by Xia & He Publishing in Journal of Clinical and Translational Hepatology
- Vol. 000 (000) , 000
Abstract
Syntaxin 5 (STX5) is a member of the syntaxin or target-soluble SNAP receptor (t-SNARE) family and plays a critical role in autophagy. However, its function and molecular mechanism in tumor cell migration are still unknown. The role of STX5 in influencing hepatocellular carcinoma (HCC) is an important topic in our research.Keywords
This publication has 41 references indexed in Scilit:
- Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complexJournal of Cell Science, 2011
- Autophagy and MetabolismScience, 2010
- The epithelial–mesenchymal transition (EMT) phenomenonAnnals of Oncology, 2010
- Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesionSeminars in Cancer Biology, 2010
- Epithelial-Mesenchymal Transitions in Development and DiseaseCell, 2009
- EMT: When epithelial cells decide to become mesenchymal-like cellsJournal of Clinical Investigation, 2009
- Membrane fusionNature Structural & Molecular Biology, 2008
- Interaction of the conserved oligomeric Golgi complex with t-SNARE Syntaxin5a/Sed5 enhances intra-Golgi SNARE complex stabilityJournal of Cell Biology, 2007
- Membrane FusionCell, 2003
- A genomic perspective on membrane compartment organizationNature, 2001