Synthesis of New Hydroxy‐2‐styrylchromones
- 19 November 2003
- journal article
- research article
- Published by Wiley in European Journal of Organic Chemistry
- Vol. 2003 (23) , 4575-4585
Abstract
Hydroxy‐2‐styrylchromones 5a−i were prepared by debenzylation of benzyloxy‐2‐styrylchromones 3a−i, which were synthesised by the Baker−Venkataraman method. The last step of this method, the cyclodehydration 5‐aryl‐3‐hydroxy‐1‐(2‐hydroxyaryl)‐2,4‐pentadien‐1‐ones 2a−i, was carried out with a catalytic amount of iodine, or p‐toluenesulfonic acid, in DMSO. Benzyloxy‐3‐cinnamoyl‐2‐styrylchromones 4a−f were obtained as by‐products in both procedures, but the latter procedure gave benzyloxy‐2‐styrylchromones 3a−i in better yields. The structures of all new compounds were established by extensive NMR studies. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)Keywords
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