Pituitary Gastrins Occur in Corticotrophs and Melanotrophs
Authors:
- 14 August 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 213 (4509) , 768-770
Abstract
The gut hormone gastrin was identified in pituitary cells containing adrenocorticotropic hormone and α-melanocyte—stimulating hormone by region-specific immunocytochemistry and radioimmunoassays. Smaller amounts of gastrin were found in nerve fibers of the neural lobe and pituitary stalk. Since adrenocorticotropic hormone—like peptides occur in antropyloric gastrin cells, these data indicate a considerable similarity in peptide composition of pituitary and gastrointestinal endocrine cells and reinforces questions of multiple hormone production.Keywords
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