Genome-wide methylation analyses of primary human leukocyte subsets identifies functionally important cell-type–specific hypomethylated regions
Open Access
- 12 December 2013
- journal article
- clinical trial
- Published by American Society of Hematology in Blood
- Vol. 122 (25) , e52-e60
Abstract
Key Points: We provide a functional DNA methylation map of human leukocyte subsets and identify cell-type–specific regulatory HMRs. We illustrate use of this data by demonstrating a potential link between gene polymorphisms, DNA methylation, and immune-mediated disease.Keywords
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