Myeloperoxidase-mediated bioactivation of 5-hydroxythiabendazole: A possible mechanism of thiabendazole toxicity
Authors:
- Joseph D. JamiesonJoseph D. Jamieson
- Evan B. SmithESEvan B. Smith
- Deepak K. DalvieDDDeepak K. Dalvie
- Gregory J. StevensGSGregory J. Stevens
- Gina M. YanochkoGina M. Yanochko
- 1 August 2011
- journal article
- Published by Elsevier in Toxicology in Vitro
- Vol. 25 (5) , 1061-1066
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Protective effects of methyl gallate on H2O2-induced apoptosis in PC12 cellsBiochemical and Biophysical Research Communications, 2010
- Bioluminescence imaging of myeloperoxidase activity in vivoNature Medicine, 2009
- IN VITRO METABOLIC ACTIVATION OF THIABENDAZOLE VIA 5-HYDROXYTHIABENDAZOLE: IDENTIFICATION OF A GLUTATHIONE CONJUGATE OF 5-HYDROXYTHIABENDAZOLEDrug Metabolism and Disposition, 2006
- Myeloperoxidase in kidney diseaseKidney International, 2003
- Identification of human cytochrome P 450 s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro dataEuropean Journal of Clinical Pharmacology, 2003
- Identification of human and rabbit cytochromes P450 1A2 as major isoforms involved in thiabendazole 5‐hydroxylationFundamental & Clinical Pharmacology, 1998
- New metabolites of thiabendazole and the metabolism of thiabendazole by mouse embryo in vivo and in vitroFood and Chemical Toxicology, 1991
- Intrahepatic cholestasis after thiabendazoleTransactions of the Royal Society of Tropical Medicine and Hygiene, 1988
- In vivo suppression of delayed hypersensitivity by thiabendazole and diethylcarbamazineImmunopharmacology, 1981
- Mitotic arrest by benzimidazole analogs in human lymphocyte culturesEnvironmental Mutagenesis, 1980