GLOMERULONEPHRITIS WITH INITIAL LUNG PURPURA (GOODPASTURE'S SYNDROME)

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Abstract
Four cases of glomerulonephritis with initial lung purpura (Goodpasture's syndrome) are presented. Two patients succumbed to their disease after a few months, one being treated with corticosteroids and hemodialysis, the other with corticosteroids only. The third patient showed complete reversal of both the pulmonary and the renal symptoms 10 months after onset of the disease. He received no chemotherapy. Now he has been in full‐time occupation for more than six months. The fourth patient, during a period of five years, experienced three episodes of glomerulonephritis with initial pulmonary hemorrhage. The symptoms, especially the hemoptysis, were far more pronounced during the first episode, and seemed to respond favorably to corticosteroid therapy. No chemotherapy was given during the last episodes. For the last 3–4 years the patient has been in good health. Patients with severe pulmonary hemorrhage and minor renal symptoms may respond favorably to corticosteroid therapy. The grave prognosis in Goodpasture's syndrome is based primarily on autopsy series. Benign forms do exist and should not be overlooked or left unpublished.

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