The HtrA stress response protease contributes to resistance of Brucella abortus to killing by murine phagocytes
Authors:
- 1 November 1996
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 64 (11) , 4838-41
Abstract
Compared with virulent Brucella abortus 2308, the isogenic htrA mutant PHE1 shows decreased resistance to killing by cultured murine neutrophils and macrophages and significant attenuation during the early stages of infection in the BALB/c mouse model. These findings further define the contributions of the htrA gene product to the pathogenesis of B. abortus infections.Keywords
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