Transient hyperphosphatasemia following gastroenteritis: avoid over-investigation in otherwise healthy children
Open Access
- 30 August 2025
- journal article
- Published by Balikesir Medical Journal in Balıkesir Medical Journal
- Vol. 9 (2) , 109-113
Abstract
Serum alkaline phosphatase concentration rises in some disease states. On the other hand, benign transient hyperphosphatasemia is most commonly recognized in infants and children younger than 2 years of age. It has also been described in adults. Benign transient hyperphosphatasemia is a self-limiting condition that is usually accompanied by some infectious and allergic disorders. Therefore it is important to keep this entity in mind to avoid unnecessary investigations. Here, we report two children who were diagnosed with benign transient hyperphosphatasemia following gastroenteritis.Keywords
This publication has 8 references indexed in Scilit:
- Benign transient hyperphosphatasemia in infants and children: a retrospective database studyEuropean Journal of Pediatrics, 2023
- Hiperfosfatasemia transitoria benigna de la infancia, Serie ClinicaRevista chilena de pediatría, 2016
- Transient Benign HyperphophatasemiaJournal of Pediatric Gastroenterology and Nutrition, 2013
- Elevated Alkaline Phosphatase in Children: An Algorithm to Determine When a “Wait and See” Approach is OptimalClinical Medicine Insights: Pediatrics, 2011
- Prevalence of Transient Hyperphosphatasemia Among Healthy Infants and ToddlersPediatrics, 2009
- Focus on Diagnosis: The Alkaline Phosphatase Level: Nuances of a Familiar TestPediatrics in Review, 2006
- What is the cause of benign transient hyperphosphatasemia? A study of 35 cases.Clinical Chemistry, 1988
- Isoenzyme Studies in Transient Hyperphosphatasemia of InfancyAmerican Journal of Diseases of Children, 1985