Full-Body Cardiovascular and Tumor MRI for Early Detection of Disease: Feasibility and Initial Experience in 298 Subjects

Authors:
  • PHPeter Hunold
    Peter Hunold
  • FVFlorian M. Vogt
    Florian M. Vogt
  • WAWaleed Ajaj
    Waleed Ajaj
  • MGMathias Goyen
    Mathias Goyen
  • CHChristoph U. Herborn
    Christoph U. Herborn
  • MFMichael Forsting
    Michael Forsting
  • JDJörg F. Debatin
    Jörg F. Debatin
  • SRStefan G. Ruehm
    Stefan G. Ruehm
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Abstract
OBJECTIVE. High diagnostic accuracy, emerging whole-body concepts, and lack of side effects combine to render MRI a natural candidate for screening purposes. The aim of this study was to evaluate the technical feasibility of a comprehensive multiorgan-targeting MRI examination and determine the frequency of findings in subjects without a history of serious disease.SUBJECTS AND METHODS. The study group was composed of 331 subjects. The MRI protocol (mean examination time, 63 min) encompassed the target organs: the brain, arterial system, heart, and colon. Diagnoses were deemed relevant if the physician had to inform the subject about the findings. Subjects with a history of serious illnesses were excluded from subsequent analysis (n = 33). All analyses were performed for the resulting subgroup of 298 subjects (247 men, 51 women; mean age, 49.7 years).RESULTS. All 298 examinations were diagnostic excluding eight MR colonography components in which remaining stool hampered reliable diagnosis. Follow-up or ra...

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