FLAIR MR Imaging for Diagnosing Intracranial Meningeal Carcinomatosis

Authors:
  • SKShichiro Katase
    Shichiro Katase
  • AYAyako Yoshino
    Ayako Yoshino
  • JHJunichi Hachiya
    Junichi Hachiya
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Abstract
OBJECTIVE. The purpose of this study was to compare unenhanced and contrast-enhanced fluid-attenuated inversion recovery (FLAIR) imaging with other sequences to visualize meningeal carcinomatosis.MATERIALS AND METHODS. Unenhanced FLAIR images were compared with spinecho T2-weighted and contrast-enhanced FLAIR images in five patients with documented meningeal carcinomatosis and four patients with suspected meningeal carcinomatosis. Comparisons were also made between contrast-enhanced T1-weighted and FLAIR images.RESULTS. In six patients, the unenhanced FLAIR images showed areas of abnormal hyperintensity within the sulci that were not noted on the spin-echo T2-weighted images. In all patients, the contrast-enhanced FLAIR images also showed meningeal enhancement, periventricular enhancement, or both. The contrast-enhanced T1-weighted and FLAIR images were equivalent in their depiction of abnormal enhancement in five of the nine patients; contrast-enhanced FLAIR images were superior in three patients.CONCLUS...

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