Molecular Evolution of Respiratory Syncytial Virus Fusion Gene, Canada, 2006–2010
Authors:
- Jesse PapenburgJPJesse Papenburg
- Julie CarbonneauJCJulie Carbonneau
- Marie-Ève HamelinMHMarie-Ève Hamelin
- Sandra IsabelSISandra Isabel
- Xavier BouhyXBXavier Bouhy
- Najwa OhoumanneNONajwa Ohoumanne
- Pierre DéryPDPierre Déry
- Bosco A. PaesBPBosco A. Paes
- Jacques CorbeilJCJacques Corbeil
- Michel G. BergeronMBMichel G. Bergeron
- Gaston De SerresGSGaston De Serres
- Guy BoivinGBGuy Boivin
Open Access
- 1 January 2012
- journal article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 18 (1) , 120-124
Abstract
To assess molecular evolution of the respiratory syncytial virus (RSV) fusion gene, we analyzed RSV-positive specimens from 123 children in Canada who did or did not receive RSV immunoprophylaxis (palivizumab) during 2006–2010. Resistance-conferring mutations within the palivizumab binding site occurred in 8.7% of palivizumab recipients and none of the nonrecipients.Keywords
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