Matrix Sublimation via In-House Developed Sublimation Apparatus v1

Authors:

JMJeffrey D. Messinger
Jeffrey D. Messinger
JAJamie Allen
Jamie Allen
KDKaterina V Djambazova
Katerina V Djambazova
AKAngela R.S. Kruse
Angela R.S. Kruse
CCChristine A. Curcio
Christine A. Curcio
KSKevin L. Schey
Kevin L. Schey
RCRichard M. Caprioli
Richard M. Caprioli
OIOlof Isberg
Olof Isberg
JSJeff Spraggins
Jeff Spraggins

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13 May 2025

preprint
Published by Springer Nature

DOI:10.17504/protocols.io.j8nlkrpq1v5r/v1

Abstract

Scope: This protocol describes the use of an in-house developed sublimation device to deposit small molecule matrices onto tissue sections for high resolution MALDI imaging mass spectrometry (IMS). Concentrations will vary based on matrix type.

Keywords

MALDI IMS
MATRIX
SUBLIMATION PROTOCOLS.IO