A New Method and a Non-Invasive Device to Estimate Anemia Based on Digital Images of the Conjunctiva
Authors:
Open Access
- 29 August 2018
- journal article
- research article
- Published by Institute of Electrical and Electronics Engineers (IEEE) in IEEE Access
- Vol. 6, 46968-46975
Abstract
Medical practice for determining haemoglobin (Hb) concentration, which is important for anemic patients in need of blood transfusion, requires a blood sample. In this paper, we propose a non-invasive approach to Hb estimation based on the image analysis of a specific conjunctival region. Our goal is to develop a device that is not expensive and simple to use for assessing the anemic condition; this device could be used by the physician to decide whether to take a blood sample or even by a patient at home to decide whether to inform a physician; in this way, we can avoid having the patient go frequently to the laboratory to take a blood sample. This device also allows us to rapidly screen for Anemia in a large number of persons, for example, groups of girls who are at the beginning of the menses. Here, we detail the prototype of our device and the methodology for extracting key information from the color values of the acquired image. Tests conducted on 113 anemic and healthy persons show a strong correlation between the real Hb value obtained through blood sampling and the value estimated by our device. A k-nearest neighbor classification algorithm for assessing the (non)anemic condition yielded good results and helps doctors avoid a significant number of blood tests.Keywords
This publication has 13 references indexed in Scilit:
- RGB pixel analysis of fingertip video image captured from sickle cell patient with low and high level of hemoglobin2017
- Examining palpebral conjunctiva for anemia assessment with image processing methodsComputer Methods and Programs in Biomedicine, 2016
- Validity of Palmar Pallor for Diagnosis of Anemia among Children Aged 6–59 Months in North IndiaAnemia, 2014
- SLIC Superpixels Compared to State-of-the-Art Superpixel MethodsIEEE Transactions on Pattern Analysis and Machine Intelligence, 2012
- Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993–2005Public Health Nutrition, 2009
- Non-Invasive Determination of Hemoglobin by Digital Photography of Palpebral ConjunctivaThe Journal of Emergency Medicine, 2007
- Image-based skin color and texture analysis/synthesis by extracting hemoglobin and melanin information in the skinACM Transactions on Graphics, 2003
- Understanding the color of human skin2001
- The Relation of Conjunctival Pallor to the Presence of AnemiaJournal of General Internal Medicine, 1997
- Test of a Noninvasive Instrument for Measuring Hemoglobin ConcentrationInternational Journal of Technology Assessment in Health Care, 1989