Influence of Sex and Race on Mycophenolic Acid Pharmacokinetics in Stable African American and Caucasian Renal Transplant Recipients
- 16 December 2014
- journal article
- research article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 54 (4) , 423-434
Abstract
No evaluation of sex and race influences on mycophenolic acid (MPA) pharmacokinetics and adverse effects (AEs) during enteric-coated mycophenolate sodium (ECMPS) and tacrolimus immunosuppression are available. The primary objective of this study was to investigate the influence of sex and race on MPA and MPA glucuronide (MPAG) pharmacokinetics in stable renal transplant recipients receiving ECMPS and tacrolimusKeywords
This publication has 56 references indexed in Scilit:
- Race and Drug Formulation Influence on Mycophenolic Acid Pharmacokinetics in Stable Renal Transplant RecipientsThe Journal of Clinical Pharmacology, 2013
- Does reduction in mycophenolic acid dose compromise efficacy regardless of tacrolimus exposure level? An analysis of prospective data from the Mycophenolic Renal Transplant (MORE) RegistryClinical Transplantation, 2012
- The Evolution of Population Pharmacokinetic Models to Describe the Enterohepatic Recycling of Mycophenolic Acid in Solid Organ Transplantation and Autoimmune DiseaseClinical Pharmacokinetics, 2011
- Comparing Mycophenolate Mofetil Regimens for de Novo Renal Transplant Recipients: The Fixed-Dose Concentration-Controlled TrialTransplantation, 2008
- Clinical Pharmacokinetics and Pharmacodynamics of Mycophenolate in Solid Organ Transplant RecipientsClinical Pharmacokinetics, 2007
- Ethnic or Racial Differences RevisitedClinical Pharmacokinetics, 2006
- Population Pharmacokinetics and Bayesian Estimation of Mycophenolic Acid Concentrations in Stable Renal Transplant PatientsClinical Pharmacokinetics, 2004
- The Influence of Sex on PharmacokineticsClinical Pharmacokinetics, 2003
- Enterohepatic CirculationClinical Pharmacokinetics, 2002
- Sex differences in drug conjugation and their consequences for drug toxicity. Sulfation, glucuronidation and gluthatione conjugationChemico-Biological Interactions, 1986