Magnetic resonance imaging in spondyloarthritis
Authors:
- Helena Marzo-OrtegaHelena Marzo-Ortega
- Dennis McGonagleDMDennis McGonagle
- Alexander N BennettABAlexander N Bennett
- 2 July 2010
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Rheumatology
- Vol. 22 (4) , 381-387
Abstract
The study of the early involvement of the axial skeleton has dominated the research map in spondyloarthritides (SpA) in recent months. MRI remains the imaging method of choice to visualize the sacroiliac joint and spine as recognized by the new classification criteria for axial SpA. This review synthesises the most recently published data and offers a critical appraisal of findings. MRI studies of inflammatory back pain of short duration have identified disease starting simultaneously in the lumbar spine and sacroiliac joints in a proportion of patients and confirm MRI as a reliable measure to assess efficacy of biologic agents in early axial SpA. The new Assessment of SpondyloArthritis International Society classification criteria can be applied in the presence and absence of radiographic abnormalities of the sacroiliac joints. Imaging studies of the spine have confirmed the diagnostic utility of spinal MRI in SpA and have described highly specific lesions such as inflammatory vertebral and posterior element lesions or the postinflammatory fatty Romanus lesions. MRI in axial SpA is the most rapidly expanding area of translational research in SpA. The publication of the new Assessment of SpondyloArthritis International Society classification criteria for axial SpA heralds a new era for the identification of early disease and mirrors the existing use of MRI in clinical practice for the evaluation of inflammatory back pain.Keywords
This publication has 36 references indexed in Scilit:
- Clinical implication of 18F-fluorodeoxyglucose PET/CT in monitoring disease activity in spondyloarthritisRheumatology, 2010
- The evidence for whole-spine MRI in the assessment of axial spondyloarthropathyRheumatology, 2010
- Positron emission tomography/computed tomography: a clinical tool for evaluation of enthesitis in patients with spondyloarthritidesRheumatology, 2009
- The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selectionAnnals of the Rheumatic Diseases, 2009
- The Assessment of SpondyloArthritis international Society (ASAS) handbook: a guide to assess spondyloarthritisAnnals of the Rheumatic Diseases, 2009
- MRI bone oedema scores are higher in the arthritis mutilans form of psoriatic arthritis and correlate with high radiographic scores for joint damageArthritis Research & Therapy, 2009
- Just released from the ASAS factory! First steps towards a disease activity score for ankylosing spondylitisAnnals of the Rheumatic Diseases, 2009
- Severity of baseline magnetic resonance imaging–evident sacroiliitis and HLA–B27 status in early inflammatory back pain predict radiographically evident ankylosing spondylitis at eight yearsArthritis & Rheumatism, 2008
- The relationship between inflammation and new bone formation in patients with ankylosing spondylitisArthritis Research & Therapy, 2008
- Evaluation of Diagnostic Criteria for Ankylosing SpondylitisArthritis & Rheumatism, 1984