Asymmetric synthesis of taxol arid taxotère side chains by enolate hydroxylation
Authors:
- Stephen HanessianSHStephen Hanessian
- Jean-Yves SancéauJSJean-Yves Sancéau
- 1 April 1996
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 74 (4) , 621-624
Abstract
We report an asymmetric synthesis of the taxol and taxotère side chains by hydroxylation of enolates derived from N-substitued methyl 3-amino-3-phenyl propionate with the oxodiperoxymolybdenum (pyridine) (hexamethyl phosphoric triamide) complex (MoOPH). Key words: taxol and taxotère side chains, hydroxylation.Keywords
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