Designing NPC1 inhibitors to halt Ebola virus progression: disrupting the hydrophobic loop-cavity interaction between NPC1-C and GPcl using combined molecular dynamics and experimental inhibitor comparison
Authors:
- 18 August 2026
- journal article
- research article
- Published by Taylor & Francis in Molecular Simulation
- Vol. 52 (14) , 1225-1255
Abstract
1. Originally named ‘Zaire’ Ebola virus (EBOV), belonging to the Filoviridae family [1], the virus induces a severe haemorrhagic fever in both humans and nonhuman primates, presenting exceptional c...Keywords
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