Lectin histochemistry of cystic jaw lesions: an aid for differential diagnosis between cystic ameloblastoma and odontogenic cysts

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Abstract
The binding sites for Ulex europaeus agglutinin I (UEA‐I), Bandeirea simplicifolia agglutinin I (BSA‐I), and peanut agglutinin (PNA) were comparatively examined in the surgical materials from 41 cases of cystic and solid ameloblastomas and 42 cases of non‐neoplastic odontogenic cysts including dentigerous cyst, odontogenic keratocyst, and radicular cyst. In non‐neoplastic cysts, most of epithelial lining layers gave positive binding with UEA‐I and BSA‐I. However, no positive reactions were obtained for these two lectins in the epithelial components of ameloblastoma, except for limited UEA‐I binding to markedly keratinized tumor cells in four cases. PNA binding was irregular and did not make any clear distinction between ameloblastomas and cysts. The results suggest that the lectin staining for UEA‐I and BSA‐I is a useful histologic aid for differential diagnosis between cystic ameloblastoma and non‐neoplastic jaw cysts.

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