Synthesis of Nitro Derivatives of Pyrocatechin as Potential Biologically Active Precursors

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Abstract
Aromatic nitro compounds are important intermediates in synthetic organic chemistry. In this work, catechol was used as raw materials, and nitro‐catechol derivatives with different alkylation substitutions were synthesized using two different synthetic routes. More than 15 new previously undescribed compounds were obtained. Each compound was meticulously characterized using a suite of physicochemical techniques, with selective compounds further analyzed via X‐Ray diffraction to ascertain their structure. These newly synthesized compounds hold significant promise as candidates for further chemical modification, which underlines their potential usefulness in the field of the fine synthesis of organic compounds.

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