Renal tubular dysfunction caused by dietary hexachlorocyclohexane (HCH) isomers
Authors:
- K. SrinivasanKSK. Srinivasan
- H.P. RameshHRH.P. Ramesh
- R. RadhakrishnamurtyRRR. Radhakrishnamurty
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Journal of Environmental Science and Health, Part B
- Vol. 19 (4-5) , 453-466
Abstract
Dietary administration of .beta.- and .gamma.-BHC to albino rats caused and abnormal excessive excretion of glucose in the urine with blood glucose level being nearly normal. Occurrence of glucosuria was also accompanied by increased excretions of the 2 low-threshold compounds, creatinine and urea with their levels in blood being normal. The interference of BHC isomers with renal function as evidenced by biochemical data was also indicated by histopathological lesions observed in the kidney sections, hypertrophy and degeneration of the renal tubular epithelia.Keywords
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