Fibrinolytic activity and clotting factors in ischaemic heart disease in women

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Abstract
The Northwick Park heart study included 695 women aged 40-64 at entry in 1972-8. The methods and assessment of deaths attributed to ischaemic heart disease were as described for the men.1 By the end of 1994, 74 women had died: 19 from ischaemic heart disease, 16 from other cardiovascular diseases, 28 from cancer, and 11 from other causes. Fibrinolytic activity is calculated as 100/(time to clot lysis in dilute whole blood (hours)),1 and lysis time was measured in 17 of the women who died from ischaemic heart disease. Results have been adjusted to age 50.