Protocol for generating liver organoids containing Kupffer cells using human iPSCs
Open Access
- 11 October 2025
- journal article
- Published by Elsevier in STAR Protocols
- Vol. 6 (4) , 104138
Abstract
No abstract availableKeywords
Funding Information
- Japan Agency for Medical Research and Development (JP 21K16377)
- Japan Agency for Medical Research and Development (JP 22bm0304002)
- Japan Agency for Medical Research and Development (JP 22bk0104102)
- Japan Agency for Medical Research and Development (JP24H00641)
- Japan Agency for Medical Research and Development (JP23bm1223007)
- Japan Agency for Medical Research and Development (JP 22fk0210073)
- Japan Agency for Medical Research and Development (JP 22bm0804004)
- Japan Agency for Medical Research and Development (JP 20K22946)
- Japan Agency for Medical Research and Development (JP 24ym0126803)
- Japan Agency for Medical Research and Development (JP 23fk0210129)
- Japan Society for the Promotion of Science London (JP24H00641)
- Institute of Medical Science, University of Tokyo
This publication has 6 references indexed in Scilit:
- Protocol for generating a pancreatic cancer organoid associated with heterogeneous tumor microenvironmentSTAR Protocols, 2025
- Integration of Kupffer cells into human iPSC-derived liver organoids for modeling liver dysfunction in sepsisCell Reports, 2024
- Heterogeneity and Function of Kupffer Cells in Liver InjuryFrontiers in Immunology, 2022
- Early Human Hemogenic Endothelium Generates Primitive and Definitive Hematopoiesis In VitroStem Cell Reports, 2018
- Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem CellsCell Reports, 2017
- Liver RegenerationScience, 1997