Scintigraphic control of bone-fracture healing under ultrasonic stimulation: An animal experimental study

Authors:

1 April 1986

journal article
research article
Published by Springer Nature in European Journal of Nuclear Medicine and Molecular Imaging

Vol. 11 (12) , 494-497
DOI:10.1007/bf00252796
PMID:3089791

Abstract

In a model of closed lower-leg fracture in rabbits and of secondary bone-fracture healing, scintigraphic control until biological healing was performed. Biological fracture healing was assumed for a region of interest (ROI)-activity ratio close to 1.0. After application of ^99mTc-HEDP, 151 examinations were performed. ROI activity increased significantly until day 14 p.i. and reached the maximum value (Q=6.44) on day 14 postfracture. Sixty-one lower leg fractures were treated by ultrasound from days 14–28 postfracture. These stimulated fractures were biologically healed on day 168 postfracture. The fractures that were not treated by ultrasound could not be detected by scanning after day 203 postfracture.

Keywords

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