Association of Infectious Mononucleosis in Childhood and Adolescence With Risk for a Subsequent Multiple Sclerosis Diagnosis Among Siblings
Open Access
- 11 October 2021
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Network Open
- Vol. 4 (10) , e2124932
Abstract
Infectious mononucleosis (IM) is a clinical manifestation of viral infection, predominantly caused by Epstein-Barr virus (EBV). Both IM and high levels of anti-EBV nuclear antigen 1 (EBNA-1) antibodies are associated with an increased risk for multiple sclerosis (MS).1,2Keywords
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