Adverse effect of verapamil in myasthenia gravis
Authors:
- 1 March 1992
- journal article
- case report
- Published by Wiley in Muscle & Nerve
- Vol. 15 (3) , 396-398
Abstract
Verapamil, a class IV anti‐arrhythmic drug that blocks voltage‐dependent calcium channels in cardiac and smooth muscle, also has effects on presynaptic and postsynaptic voltage‐dependent calcium channels at the neuromuscular junction. In a postoperative patient with pre‐existent myasthenia gravis, oral verapamil caused a marked exacerbation in myasthenic weakness.Keywords
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