Antitumour alkaloids of the vinblastine-type: is leurosine an artefact?
Authors:
- Nicole LangloisNLNicole Langlois
- Pierre PotierPPPierre Potier
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 3,p. 102-103
Abstract
The Δ15′(20′) double bond of anhydrovinblastine (1) is oxidized by various oxidants, in particular by air, to give the corresponding epoxide leurosine (5); the question of leurosine (5) being an artefact is discussed.Keywords
This publication has 1 reference indexed in Scilit:
- Application of a modification of the Polonovski reaction to the synthesis of vinblastine-type alkaloidsJournal of the American Chemical Society, 1976