Molecular similarities between the Qa-2 alloantigen and other gene products of the 17th chromosome of the mouse.

Authors:
  • JMJ Michaelson
    J Michaelson
  • LFL Flaherty
    L Flaherty
  • EVE Vitetta
    E Vitetta
  • MPM D Poulik
    M D Poulik

Abstract
The alloantigen Qa-2, whose gene is located on the 17th chromosome between H-2D and Tla, is identified as a molecule of 43,000 daltons which is associated with .beta.2-microglobulin. Qa-2 comprises approximately 0.15% of the iodinateable cell surface protein of lymph node cells. Sequential precipitations demonstrated that Qa-2 is distinct from H-2D and H-2K molecules.

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