Association Between Sleep Apnea Syndrome and Nonarteritic Anterior Ischemic Optic Neuropathy
Authors:
- Thomas R. HedgesTHThomas R. Hedges
- Bruce EhrenbergBEBruce Ehrenberg
- Emely Z. KaramEKEmely Z. Karam
- David GoldblumDGDavid Goldblum
- Alex Abou-CheblAAAlex Abou-Chebl
- Matthias GuggerMGMatthias Gugger
- Johannes MathisJMJohannes Mathis
Open Access
- 1 May 2002
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 120 (5) , 601-605
Abstract
NONARTERITIC anterior ischemic optic neuropathy (NAION) is a disease characterized by sudden, painless, mostly irreversible, and generally nonprogressive visual loss accompanied by nerve fiber bundle field defects, a relative afferent pupillary defect, and optic disc edema. The pathophysiologic characteristics of NAION remains unclear. Although several risk factors have been associated with this relatively common condition, the exact mechanism(s) that lead to optic nerve infarction remain unknown. Risk factors include aging, a small optic nerve head, and microvascular changes associated with diabetes and systemic hypertension.1 No treatment is available since neither steroids nor surgical optic nerve sheath fenestration has proved to be effective. Prevention with aspirin has not been demonstrated to be effective, although it is recommended.2Keywords
This publication has 19 references indexed in Scilit:
- Eyelid, conjunctival, and corneal findings in sleep apnea syndromeOphthalmology, 1999
- High prevalence of glaucoma in patients with sleep apnea syndromeOphthalmology, 1999
- Optic neuropathy associated with sleep apnea syndromeOphthalmology, 1998
- Nonarteritic Anterior Ischemic Optic Neuropathy: Time of Onset of Visual LossAmerican Journal of Ophthalmology, 1997
- Sleep-Related Myocardial Ischemia and Sleep Structure in Patients With Obstructive Sleep Apnea and Coronary Heart DiseaseChest, 1997
- Sleep Apnea Syndrome and Cerebral HemodynamicsChest, 1996
- 24-Hour Blood Pressure Monitoring in Patients With Anterior Ischemic Optic NeuropathyArchives of Ophthalmology (1950), 1996
- The Sleep Disorders Questionnaire I: Creation and Multivariate Structure of SDQSLEEP, 1994
- Nocturnal Hypotension in Older Men with Sleep-Related Breathing DisordersChest, 1988
- Optic Nerve Swelling Secondary to the Obstructive Sleep Apnea SyndromeAmerican Journal of Ophthalmology, 1988