Improved Cancer Detection Using Computer-Aided Detection with Diagnostic and Screening Mammography: Prospective Study of 104 Cancers
Authors:
- 1 July 2006
- journal article
- Published by American Roentgen Ray Society in American Journal of Roentgenology
- Vol. 187 (1) , 20-28
Abstract
OBJECTIVE. This study prospectively evaluated a computer-aided detection (CAD) device used with diagnostic and screening mammography by assessing cancers detected; tumor sizes, histology, and stage; positive predictive value (PPV) of biopsy recommendation; and recall rates before and after CAD introduction.SUBJECTS AND METHODS. Interpretations of 9,520 consecutive mammograms were recorded without and then with CAD for a 28-month period. Cancer detections based on initial radiologist review and additional detections based on CAD findings were noted. Recall rates, tumor size and histology, and PPV of biopsy recommendation before and after the introduction of CAD were compared.RESULTS. Cancers detected only with CAD assistance were 9.6% of all cancers (10 of 104); screening-detected cancers increased 13.3% with CAD assistance (four in addition to 30 screening-detected cancers). The 95% one-sided confidence boundary using binomial distribution is consistent with at least 5.3% for all cancers and 5.1% for nonp...Keywords
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