ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS
Authors:
Open Access
- 1 August 1962
- journal article
- research article
- Published by Rockefeller University Press in Journal of Experimental Medicine
- Vol. 116 (2) , 177-186
Abstract
In rats thymectomized at birth and tested in adult life, ability to develop autoallergic encephalomyelitis was completely suppressed, there was a marked diminution in the degree of tuberculin sensitization appearing after a single injection of mycobacteria in oil, rejection of skin homografts was markedly delayed, and adjuvant arthritis was not appreciably affected. At the same time there was a striking decrease in the circulating level of small lymphocytes.Keywords
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