Long‐term Hypotensive Effect of Atenolol (ICI 66.082), a New β‐adrenergic Blocking Agent

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Abstract
A report is given from an on‐going multicenter trial in Sweden, in which 117 hypertensive patients have been treated with a new cardioselective β‐adrenergic blocking agent, atenolol (ICI 66.082, Tenormin®) for an average of six months (range 2–21). Statistically significant reductions of BP were observed, recumbent by 29/19 mmHg (p < 0.0001) and standing by 28/18 mmHg (p < 0.0001). Few and comparatively mild sideeffects were seen.