Sensorineural hearing loss at 9-13 years of age in children with a history of neonatal extracorporeal membrane oxygenation

Authors:
  • TNToni Nield
    Toni Nield
  • CLClaudine Larson-Tuttle
    Claudine Larson-Tuttle
  • ISIstvan Seri
    Istvan Seri
  • PFPhilippe Friedlich
    Philippe Friedlich
Publisher website
Google Scholar
Abstract
Objective To investigate the incidence of late-onset sensorineural hearing loss (SNHL) and study the association between neonatal extracorporeal membrane oxygenation (ECMO) and SNHL in survivors of neonatal ECMO between 9 and 13 years of age. Study design Retrospective analysis of medical records of 212 neonatal ECMO survivors treated between 1987 and 1991 to identify children with complete hearing evaluation at 9–13 years of age. Patients were categorised into normal hearing (NH) and SNHL groups. Cox proportional-hazard regression analysis was used to take into account the variable age at follow-up and to assess the independent effect of each risk factor for SNHL. Results Forty-eight of the 212 patients had complete hearing evaluations at 9–13 years of age and eight of 48 patients were diagnosed as having SNHL. In two patients, SNHL was first detected between 9 and 13 years. A significant difference between the SNHL and NH groups was found in median 5 min Apgar scores, mean ECMO support duration, proportion of infants with pre-ECMO Paco2 of Conclusion Clinical seizure activity prior to ECMO and the duration of ECMO therapy are independently associated with SNHL. These data confirm that there is an increased incidence of SNHL in neonatal ECMO survivors at 9–13 years of age and suggest that SNHL may also present later in childhood in this patient population. Upon recovery from acute respiratory failure and after discharge from the hospital, longitudinal neurodevelopmental follow-up of infants treated with ECMO during the neonatal period is essential.

This publication has 21 references indexed in Scilit: