Significance of Apparent Half-Lives of a Metabolite with a Higher Elimination Rate Than its Parent Drug
Authors:
- Tom B. VreeTVTom B. Vree
- Chiel A. HeksterCHChiel A. Hekster
- Eppo van der KleijnEKEppo van der Kleijn
- 1 February 1982
- journal article
- Published by SAGE Publications in Drug Intelligence & Clinical Pharmacy
- Vol. 16 (2) , 126-131
Abstract
No abstract availableThis publication has 10 references indexed in Scilit:
- Factors influencing the activity and fate of benzodiazepines in the body.1981
- Renal Excretion of Sulphamethoxazole and Its Metabolite N4-Acetylsulphamethoxazole in Patients with Impaired Kidney FunctionTherapeutic Drug Monitoring, 1981
- Diastereoisomeric glucuronides of oxazepam. Isolation and stereoselective enzymic hydrolysis.Drug Metabolism and Disposition, 1979
- Pharmacokinetics and Bioavailability of Intravenous, Intramuscular, and Oral Lorazepam in HumansJournal of Pharmaceutical Sciences, 1979
- Pharmacokinetics of N1-Acetyl- and N4-Acetylsulphamethoxazole in ManClinical Pharmacokinetics, 1979
- Pharmacokinetics of Sulphamethoxazole in ManClinical Pharmacokinetics, 1978
- Pharmacokinetics of Biotransformation1977
- Kinetics of Drug Action1977
- Sulphamethoxazole/trimethoprim: Pharmacokinetic studies in patients with chronic renal failureEuropean Journal of Clinical Pharmacology, 1972
- Acetylation and deacetylation of the p-amino group of sulphonamide drugs in animal tissuesBiochemical Journal, 1947