Exclusion of the gelsolin gene on 9q32-34 as the cause of familial lattice corneal dystrophy type I.
Authors:
- S MarlesSMS Marles
- J SafneckJSJ Safneck
- D J KwiatkowskiDKD J Kwiatkowski
- C P MauryCMC P Maury
- T ZelinskiTZT Zelinski
- S PhilippsSPS Philipps
- M B EkinsMEM B Ekins
- C R GreenbergCGC R Greenberg
- 1 July 1992
- journal article
- Vol. 51 (1) , 156-60
Abstract
Familial lattice corneal dystrophy type I (LCD1) is a localized form of inherited amyloidosis limited to the corneal stroma. Recently the Finnish form of hereditary amyloidosis with lattice corneal dystrophy has been shown to be due to a mutation in the gelsolin gene (G654----A; Asp187----Asn). In this paper we exclude the gelsolin gene as the cause of the autosomal dominant form of isolated LCD1.Keywords
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