Selective cleavage of unactivated arene ring C–C bonds by iridium: key roles of benzylic C–H activation and metal–metal cooperativity
Open Access
- 12 January 2021
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Science
- Vol. 12 (10) , 3568-3579
Abstract
The detailed mechanism of iridium-mediated C–C cleavage in unactivated arenes reveals the key factors enabling the process and helps predict the scope of the cleavage reaction.Keywords
Funding Information
- Leverhulme Trust (RPG-2018-406)
- Engineering and Physical Sciences Research Council (EP/ L000075/1)
This publication has 57 references indexed in Scilit:
- Metal-mediated cleavage of unsaturated C-C bondsCoordination Chemistry Reviews, 2020
- Transition‐Metal‐Mediated Cleavage of C−C Bonds in Aromatic RingsChemistry – An Asian Journal, 2019
- Recent Developments in Palladium-Catalysed Non-Directed C–H Bond Activation in ArenesSynthesis, 2019
- Arene‐Limited Nondirected C−H Activation of ArenesAngewandte Chemie International Edition, 2018
- Selective Arene Cleavage by Direct Insertion of Iridium into the Aromatic RingAngewandte Chemie International Edition, 2017
- “Cut and Sew” Transformations via Transition-Metal-Catalyzed Carbon–Carbon Bond ActivationACS Catalysis, 2017
- Undirected, Homogeneous C–H Bond Functionalization: Challenges and OpportunitiesACS Central Science, 2016
- Mild metal-catalyzed C–H activation: examples and conceptsChemical Society Reviews, 2016
- Beyond Directing Groups: Transition‐Metal‐Catalyzed C-H Activation of Simple ArenesAngewandte Chemie International Edition, 2012
- Buchner and Beyond: Arene Cyclopropanation as Applied to Natural Product Total SynthesisSynlett, 2011