Metformin has immunomodulatory effects which support its potential use as adjunctive therapy in tuberculosis

This publication has 45 references indexed in Scilit:

• Transcriptional control of effector and memory CD8+ T cell differentiation
  Nature Reviews Immunology, 2012
• Mitochondria-Ros Crosstalk in the Control of Cell Death and Aging
  Journal of Signal Transduction, 2011
• Mycobacterium tuberculosis and the intimate discourse of a chronic infection
  Immunological Reviews, 2011
• Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
  Journal of Clinical Investigation, 2010
• Cytotoxicity and Secretion of Gamma Interferon Are Carried Out by Distinct CD8 T Cells duringMycobacterium tuberculosisInfection
  Infection and Immunity, 2009
• Enhancing CD8 T-cell memory by modulating fatty acid metabolism
  Nature, 2009
• Activation of AMP-Activated Protein Kinase Reduces Hyperglycemia-Induced Mitochondrial Reactive Oxygen Species Production and Promotes Mitochondrial Biogenesis in Human Umbilical Vein Endothelial Cells
  Diabetes, 2006
• Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages
  Cell, 2004
• The AMP-activated protein kinase pathway – new players upstream and downstream
  Journal of Cell Science, 2004
• Elevated Glucose Levels Stimulate Transforming Growth Factor-β1 (TGF-β1), Suppress Interleukin IL-2, IL-6 and IL-10 Production and DNA Synthesis in Peripheral Blood Mononuclear Cells
  Hormone and Metabolic Research, 1996