Saccharomyces cerevisiae Enhanced the Growth, Immune and Antioxidative Responses of European Seabass ( Dicentrarchus labrax )

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Abstract
The concept of probiotics is widely applied in the field of aquaculture for their beneficial and friendly influences. In this sense, the role of Saccharomyces cerevisiae on the growth, immune and antioxidative responses of European seabass was tested in this study. Fish were distributed in 3 groups (triplicates) with ten fish in each replicate and fed 0, 1, and 2 g/kg of S. cerevisiae (15×10 9 CFU/g) for 90 days. Fish fed S. cerevisiae showed higher final body, weight gain, and specific growth rate as well as lower FCR than fish fed the basal diet (PS. cerevisiae when compared to the control (PS. cerevisiae than the control (PS. cerevisiae had enhanced phagocytic index, phagocytic, and lysozyme activity comparing the control. In a similar sense, the antioxidative enzymes (SOD, GPx, and CAT) were higher in fish fed S. cerevisiae than the control (PS. cerevisiae in European seabass. Gene expression of IL-8 , IL-1β , GH , and IGF-1 was upregulated and HSP70 was downregulated by S. cerevisiae (PS. cerevisiae at 1–2 g/kg (15×10 9 CFU/g) diet had markedly enhanced growth, haemato-biochemical, and immune performances.

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