European task force on atopic dermatitis position paper: treatment of parental atopic dermatitis during preconception, pregnancy and lactation period
- 23 June 2019
- journal article
- research article
- Published by Wiley in Journal of the European Academy of Dermatology and Venereology
- Vol. 33 (9) , 1644-1659
Abstract
Atopic dermatitis (AD) is a common inflammatory skin disease that affects both children and adults, including a large number of adults of reproductive age. Several guidelines for the treatment of AD exist, yet specific recommendations for the treatment of pregnant or lactating women and for adults planning to have a child are often lacking. This position paper from the European Task force on Atopic Dermatitis (ETFAD) is based on up‐to‐date scientific literature on treating pregnant and lactating women as wells as adults with AD planning to have a child. It is based on the expert opinions of members of the ETFAD and on existing safety data on the proposed treatments, many of which are derived from patients with other inflammatory diseases or from transplantation medicine. For treating future parents, as well as pregnant and lactating women with AD, the use of topical treatments including moisturizers, topical corticosteroids, tacrolimus, antiseptics such as chlorhexidine, octenidine, potassium permanganate and sodium hypochlorite (bleach) is deemed to be safe. Ultraviolet (UV) therapy may also be used. Systemic treatment should be prescribed only after careful consideration. According to the opinion of the ETFAD, treatment should be restricted to systemic corticosteroids and cyclosporine A, and, in selected cases, azathioprine.Keywords
This publication has 120 references indexed in Scilit:
- Immunology of atopic eczema: overcoming the Th1/Th2 paradigmAllergy, 2013
- Alcohol Intake in Pregnancy Increases the Child's Risk of Atopic Dermatitis. The COPSAC Prospective Birth Cohort Study of a High Risk PopulationPLOS ONE, 2012
- Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitisGenome Research, 2012
- Long Term Treatment Concepts and Proactive Therapy for Atopic EczemaAnnals of Dermatology, 2012
- Corticosteroid use during pregnancy and risk of orofacial cleftsCanadian Medical Association Journal, 2011
- Effect of narrowband ultraviolet B phototherapy on serum folic acid levels in patients with psoriasisLasers in Medical Science, 2011
- Managing pregnancy in inflammatory rheumatological diseasesArthritis Research & Therapy, 2011
- The use of cyclosporine in dermatology: Part IJournal of the American Academy of Dermatology, 2010
- The use of cyclosporine in dermatology: Part IIJournal of the American Academy of Dermatology, 2010
- Pharmacokinetics of topical calcineurin inhibitors in adult atopic dermatitis: A randomized, investigator-blind comparisonJournal of the American Academy of Dermatology, 2005