Aberrant Overexpression of the Rgl2 Ral Small GTPase-specific Guanine Nucleotide Exchange Factor Promotes Pancreatic Cancer Growth through Ral-dependent and Ral-independent Mechanisms
Authors:
- Timothy D. MartinTMTimothy D. Martin
- Falina WilliamsFWFalina Williams
- Jen Jen YehJYJen Jen Yeh
- Sharon L. CampbellSCSharon L. Campbell
- Channing J. DerCDChanning J. Der
Open Access
- 1 November 2010
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 285 (45) , 34729-34740
Abstract
No abstract availableKeywords
This publication has 58 references indexed in Scilit:
- Tuberous Sclerosis Tumor Suppressor Complex-like Complexes Act as GTPase-activating Proteins for Ral GTPasesJournal of Biological Chemistry, 2009
- Proteasomal and Genetic Inactivation of the NF1 Tumor Suppressor in GliomagenesisCancer Cell, 2009
- Rho Family GTPase Modification and Dependence on CAAX Motif-signaled Posttranslational ModificationJournal of Biological Chemistry, 2008
- Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFsThe EMBO Journal, 2008
- Cortactin in tumor invasivenessCancer Letters, 2008
- p120 catenin regulates lamellipodial dynamics and cell adhesion in cooperation with cortactinProceedings of the National Academy of Sciences, 2007
- GEFs and GAPs: Critical Elements in the Control of Small G ProteinsCell, 2007
- R-Ras Regulates Exocytosis by Rgl2/Rlf-mediated Activation of RalA on EndosomesMolecular Biology of the Cell, 2007
- Akt–PDK1 Complex Mediates Epidermal Growth Factor-induced Membrane Protrusion through Ral ActivationMolecular Biology of the Cell, 2007
- Cortactin Promotes Cell Motility by Enhancing Lamellipodial PersistenceCurrent Biology, 2005