Quantification of the ocular reactions to microfilaricides in the chemotherapy of onchocerciasis
Authors:
- 1 January 1992
- journal article
- Published by Springer Nature in Eye
- Vol. 6 (1) , 93-96
Abstract
Severe adverse systemic and ocular reactions have complicated the chemotherapy of onchocerciasis. A method for the quantification of ocular reactions to chemotherapy has been devised at the Onchocerciasis Chemotherapy Research Centre, at Hohoe, in Ghana. Symptoms, visual function, anterior segment inflammation and disease of the posterior segment are graded. The information is entered into a computerised database which allows reaction scores to be calculated both for individual patients, and for treatment groups. This system enables comparision of adverse ocular reactions to various new chemotherapeutic regimens.Keywords
This publication has 8 references indexed in Scilit:
- Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.British Journal of Ophthalmology, 1987
- Comparison of Ivermectin and Diethylcarbamazine in the Treatment of OnchocerciasisNew England Journal of Medicine, 1985
- Ocular and Systemic Complications of Diethylcarbamazine Therapy for Onchocerciasis: Association with Circulating Immune ComplexesThe Journal of Infectious Diseases, 1983
- Ocular changes with oral and transepidermal diethylcarbamazine therapy of onchocerciasis.British Journal of Ophthalmology, 1981
- The chemotherapy of onchocerciasis IIIPathogens and Global Health, 1980
- Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.British Journal of Ophthalmology, 1980
- Dangerous reactions to treatment of onchocerciasis with diethylcarbamazine.BMJ, 1977
- Morphology of posterior segment lesions of the eye in patients with onchocerciasis.British Journal of Ophthalmology, 1976