Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside

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Abstract
Cystic fibrosis is the most common genetic disease, in which symptoms may be alleviated but not fully eliminated. Ceramides have long been implicated in th
Funding Information
  • Ministère du Développement Économique, de l'Innovationet de l'Exportation (MDEIE/MESRST)
  • Fondo Nacional de Ciencia Tecnología e Innovación (G2005000389)
  • Ministère du Développement Économique, de l'Innovationet de l'Exportation (MDEIE/MESRST) (Ministère du Développement Économique, de l'Innovationet de l'Exportation (MDEIE/MESRST))
  • Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Award
  • Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada
  • Cystic Fibrosis Canada
  • Groupe de Recherche Axé sur la Structure des Protéins (GRASP)
  • Canadian Institutes of Health Research
  • Cystic Fibrosis Foundation

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