Contemporary microbiology and identification ofCorynebacteriaspp. causing infections in human
- 24 March 2018
- journal article
- review article
- Published by Oxford University Press (OUP) in Letters in Applied Microbiology
- Vol. 66 (6) , 472-483
Abstract
The Corynebacterium genus are bacteria of growing clinical importance. It is because of progress in medicine that result in growing population of immunocompromised patients and growing number of infections caused by opportunistic pathogens. A new infections caused by Corynebacterium species regarded previously as commensal microorganisms as well as infections caused by new Corynebacterium species are described. Parallel with changes in Corynebacteria infections the microbiological laboratory diagnostic possibilities are changing. But identification of this group of bacteria to the species level remains difficult. In the paper we present various manual, semi‐automated and automated assays used in clinical laboratories for Corynebacterium identification, such as API Coryne, RapID CB Plus, BBL Crystal Gram Positive Panel, MICRONAUT‐RPO, VITEK 2, BD Phoenix System, Sherlock Microbial ID System, MicroSeq Microbial Identification System, Biolog Microbial Identification Systems, MALDI‐TOF MS systems, PCR‐based and sequencing‐based assays. The presented assays are based on various properties, like biochemical tests, specific DNA sequences, composition of cellular fatty acids, protein profiles and have specific limitations.Keywords
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