Age of introduction of complementary foods and growth of term, low-birth-weight, breast-fed infants: a randomized intervention study in Honduras
Authors:
Open Access
- 1 April 1999
- journal article
- clinical trial
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 69 (4) , 679-686
Abstract
Background: The optimal age at which to introduce complementary foods is a topic of considerable debate. Objective: This study was designed to evaluate this issue in a nutritionally vulnerable population in Honduras. Design: Mothers of low-birth-weight (1500–2500 g) term (ie, small-for-gestational-age) infants were recruited in the hospital and assisted with exclusive breast-feeding during the first 4 mo. At 4 mo, mothers were randomly assigned to either continue exclusive breast-feeding to 6 mo (EBF; n = 59) or to feed complementary solid foods (jarred rice cereal, chicken, and fruit and vegetables) twice daily from 4 to 6 mo while continuing to breast-feed at their initial frequency (SF; n = 60). At 4 and 6 mo, breast milk and total energy intake were measured for a nonrandom subsample (those who could stay overnight in a central unit: 32 EBF and 31 SF). Results: At 4 mo, breast milk intake in the subsample was not significantly different between groups (EBF: 729 ± 135 g/d; SF: 683 ± 151 g/d; P > 0.2); from 4 to 6 mo it increased (by 28 g/d) in the EBF group but decreased (by 39 g/d) in the SF group (P < 0.005). Nonetheless, total energy intake (including solid foods) increased more from 4 to 6 mo in the SF than in the EBF group. However, there were no significant differences between groups in weight or length gain during the intervention or subsequently (6–12 mo). Conclusion: There was no growth advantage of complementary feeding of small-for-gestational-age, breast-fed infants between 4 and 6 mo of age.Keywords
This publication has 10 references indexed in Scilit:
- Effects of age of introduction of complementary foods on iron status of breast-fed infants in HondurasThe American Journal of Clinical Nutrition, 1998
- Validation of single daytime samples of human milk to estimate the 24-h concentration of lipids in urban Guatemalan mothersThe American Journal of Clinical Nutrition, 1997
- Effect of early, short-term supplementation on weight and linear growth of 4–7-mo-old infants in developing countries: a four-country randomized trialThe American Journal of Clinical Nutrition, 1996
- Maternal anthropometric status and lactation performance in a low-income Honduran population: evidence for the role of infantsThe American Journal of Clinical Nutrition, 1995
- Effects of age of introduction of complementary foods on infant breast milk intake, total energy intake, and growth: a randomised intervention study in HondurasThe Lancet, 1994
- Breast-feeding and Diarrheal MorbidityPediatrics, 1990
- Infant-Feeding Practices and Their Relationship With Diarrheal and Other Diseases in Huascar (Lima), PeruPediatrics, 1989
- A simplified method for diagnosis of gestational age in the newborn infantThe Journal of Pediatrics, 1978
- The stability of sucking behavior and its relationship to intake during the first month of lifeInfant Behavior and Development, 1978
- A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUESJournal of Biological Chemistry, 1957