Benzenesulfonamide decorated dihydropyrimidin(thi)ones: carbonic anhydrase profiling and antiproliferative activity
Authors:
- Hakan AslanHAHakan Aslan
- Andrea AngeliAAAndrea Angeli
- Ilaria D'AGostinoIlaria D'AGostino
- Roberto RoncaRRRoberto Ronca
- Maria Luisa MassardiMMMaria Luisa Massardi
- Camilla TavaniCTCamilla Tavani
- Simone CarradoriSimone Carradori
- Marta FerraroniMFMarta Ferraroni
- Paolo GovernaPaolo Governa
- Fabrizio ManettiFabrizio Manetti
- Fabrizio CartaFCFabrizio Carta
Open Access
- 26 March 2024
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in RSC Medicinal Chemistry
- Vol. 15 (6) , 1929-1941
Abstract
One-step synthesis and a chemical similarity-based screening provide new tumor-associated carbonic anhydrase (CA) inhibitors for anticancer application.Keywords
Funding Information
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu (1059B192101059)
This publication has 55 references indexed in Scilit:
- Antimalarial Agents Targeting Plasmodium falciparum Carbonic Anhydrase: Towards Artesunate Hybrid Compounds with Dual Mechanism of ActionChemMedChem, 2023
- Local Anesthetics via Multicomponent ReactionsChemMedChem, 2022
- A decade of tail-approach based design of selective as well as potent tumor associated carbonic anhydrase inhibitorsBioorganic Chemistry, 2022
- Switching the Inhibitor‐Enzyme Recognition Profile via Chimeric Carbonic Anhydrase XIIChemistryOpen, 2021
- Pietro Biginelli: The Man Behind the ReactionEuropean Journal of Organic Chemistry, 2011
- Selective COX-2 inhibitors. Part 2: Synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamidesBioorganic & Medicinal Chemistry, 2008
- Carbonic anhydrase IX: A new druggable target for the design of antitumor agentsMedicinal Research Reviews, 2007
- Processing diffraction data with mosflm2007
- UCSF Chimera—A visualization system for exploratory research and analysisJournal of Computational Chemistry, 2004
- Structure validation by Cα geometry: ϕ,ψ and Cβ deviationProteins: Structure, Function, and Bioinformatics, 2003