Effects ofTET2mutations on DNA methylation in chronic myelomonocytic leukemia
- 1 February 2012
- journal article
- Published by Taylor & Francis in Epigenetics
- Vol. 7 (2) , 201-207
Abstract
TET2 enzymatically converts 5-methyl-cytosine to 5-hydroxymethyl-cytosine, possibly leading to loss of DNA methylation. TET2 mutations are common in myeloid leukemia and were proposed to contribute...Keywords
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